Human recombinant Wee1

Leverandør: Merck Millipore Calbiochem

325896-10
325896-10EA 10150 NOK
325896-10
Human recombinant Wee1
Enzymer

Recombinant, human Wee1 fused at the N-terminus to a GST-His6-thrombin cleavage site sequence and expressed in S. frugiperda insect cells using a baculovirus expression system.


Wee1 is a tyrosine kinase that causes inhibitory phosporylation of Cdk1 and Cdk2 and acts as a mitotic inhibitor. Protects the nucleus from cytoplasmically activated cyclin B1-complexed CDC2 prior to the onset of mitosis.

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