C-4 ≥95% (by HPLC), Calbiochem®, Sigma-Aldrich®

Leverandør: Merck Millipore Calbiochem

Synonymer: (E)-4-Chloro-N-(3-(3-(4-hydroxy-3-methoxyphenyl)acryloyl)phenyl)benzamide,, P-Glycoprotein Inhibitor

M-Clarity™ quality level = MQ100

517301-10
517301-10EA 3675 NOK
517301-10
C-4 ≥95% (by HPLC), Calbiochem®, Sigma-Aldrich®
C-4

The P-Glycoprotein Inhibitor, C-4 controls the biological activity of P-Glycoprotein. This small molecule/inhibitor is primarily used for Cancer applications.


General description
A cell-permeable cinnamoyl compound that reversibly inhibits P-gp (P-glycoprotein) efflux function and reverses the MDR (multidrug resistance) phenotype with no noticeable effect on P-gp expression. Shown to significantly enhance Paclitaxel- (Cat. No. 580555) and Vincristine- (Cat. No. 677181) induced cytotoxicity as well as apoptosis in P-gp expressing KBV20C cells.


Forpakning: Packaged under inert gas

Formel: C₂₃H₁₈ClNO₄
MW: 407,85 g/mol
Lagringstemperatur: Kjøleskap
CAS-nummer: 864426-22-2

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