Anti-AIFM1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Leverandør: Bioss
BS-0037R-A555
BOSSBS-0037R-A555EA 10550 NOK
BOSSBS-0037R-A555
Anti-AIFM1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
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Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis,More Product Information
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