Anti-AIFM1 Rabbit Polyclonal Antibody (Cy7®)

Leverandør: Bioss
BS-0037R-CY7
BOSSBS-0037R-CY7EA 10650 NOK
BOSSBS-0037R-CY7
Anti-AIFM1 Rabbit Polyclonal Antibody (Cy7®)
Antistoffer
Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis,More Product Information
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SPESIFIKASJONER

Antigensymbol AIFM1
Environmentally Preferable
Antigen-navn Apoptosis-Inducing Factor, Mitochondrion-Associated, 1
Antigen synonymer COWCK|NADMR|AIF|NAMSD|CMT2D|COXPD6|PDCD8|CMTX4
Antistofftype Primary
Klonalitet Polyclonal
Konjugering Cy7®
Reaktivitet Pig,Human,Rat,Mouse
Vert Rabbit
Gen-ID 9131
Isotype IgG
ImmunoKjemi Yes
Immunogen 130-180/613
Skjema liquid
Rensing Purified by Protein A
Konsentrasjon 1 μg/μl
Kyssabsorpsjon No
Lagringsbuffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Lagringstemp Store at 4°C for 12 months
Frakttemp. 4°C

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