Anti-YKL39/CHI3L2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Leverandør: Bioss
BS-12358R-A680
BOSSBS-12358R-A680EA 10425 NOK
BOSSBS-12358R-A680
Anti-YKL39/CHI3L2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
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YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases. Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), YKL-39 binds glycan structures with high affinity. Although related to bacterial chitinases, YKL-39 lacks the characteristic glutamate active site and, thus, does not have enzymatic chitinase activity. Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid jointMore Product Information
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