Anti-GRB7 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Leverandør: Bioss
BS-13642R-A750
BOSSBS-13642R-A750EA 10425 NOK
BOSSBS-13642R-A750
Anti-GRB7 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
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Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1,2). Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3,4). GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N-terminus (5,6). GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6). This region of mouseMore Product Information
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