Anti-ABI1 Rabbit Polyclonal Antibody

Leverandør: Bioss
BS-1961R
BOSSBS-1961REA 8500 NOK
BOSSBS-1961R
Anti-ABI1 Rabbit Polyclonal Antibody
Antistoffer
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodiaMore Product Information
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SPESIFIKASJONER

Antigensymbol ABI1
Antigen-navn Abl-Interactor 1
Environmentally Preferable
Antigen synonymer Spectrin SH3 domain-binding protein 1|Abl-binding protein 4|SSH3BP|Eps8 SH3 domain-binding protein|Abl interactor 1|Nap1-binding protein|E3B1|Abelson interactor 1|SSH3BP1|ABLBP4|NAP1BP|ABI-1
Antistofftype Primary
Klonalitet Polyclonal
Konjugering Unconjugated
Reaktivitet Human,Rat,Mouse
Vert Rabbit
Gen-ID 10006
Isotype IgG
Western blot Yes
ImmunoKjemi Yes
Immunogen 140-190/508
Skjema liquid
Rensing Purified by Protein A.
Konsentrasjon 1 ug/ul
Lagringsbuffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
Frakttemp. 4 °C

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