Anti-ABI1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Leverandør: Bioss
BS-1961R-A750
BOSSBS-1961R-A750EA 10425 NOK
BOSSBS-1961R-A750
Anti-ABI1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antistoffer
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodiaMore Product Information
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SPESIFIKASJONER

Antigen-navn ABI1
Environmentally Preferable
Antigen synonymer Spectrin SH3 domain-binding protein 1|Abl-binding protein 4|SSH3BP|Eps8-binding protein|Eps8 SH3 domain-binding protein|Abl interactor 1|Nap1-binding protein|E3B1|Abelson interactor 1|SSH3BP1|ABLBP4|ABI1|NAP1BP|ABI-1
Antistofftype Primary
Klonalitet Polyclonal
Konjugering Alexa Fluor® 750
Reaktivitet Rat
Vert Rabbit
Gen-ID 10006
Isotype IgG
Western blot Yes
ImmunoKjemi Yes
ImmunoFluorescens Yes
Modifikasjon Unmodified
Epitop 101-200/508
Immunogen KLH conjugated synthetic peptide derived from human ABI1
Skjema Liquid
Molekylvekt 55 kDa
Rensing Purified by Protein A
Konsentrasjon 1 µg/µl
Lagringsbuffer Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Lagringstemp Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Frakttemp. 4 °C
Uttestet applikasjon ICC

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