Anti-ABI1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Leverandør: Bioss
BS-1961R-HRP
BOSSBS-1961R-HRPEA 10550 NOK
BOSSBS-1961R-HRP
Anti-ABI1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Antistoffer
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodiaMore Product Information
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