Anti-DRES17 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Leverandør: Bioss
BS-6299R-A750
BOSSBS-6299R-A750EA 10450 NOK
BOSSBS-6299R-A750
Anti-DRES17 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antistoffer
PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

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