Anti-SHOC2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Leverandør: Bioss
BS-7934R-A750
BOSSBS-7934R-A750EA 10450 NOK
BOSSBS-7934R-A750
Anti-SHOC2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antistoffer
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialised signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. AffectedMore Product Information
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SPESIFIKASJONER

Environmentally Preferable
Antigen-navn SHOC2
Antigen synonymer SHOC2_HUMAN|Ras-binding protein Sur-8|Leucine-rich repeat protein SHOC-2|KIAA0862|Protein Sur-8 homolog|SHOC2|Protein soc-2 homolog
Antistofftype Primary
Klonalitet Polyclonal
Konjugering Alexa Fluor® 750
Reaktivitet Human,Rat,Mouse
Vert Rabbit
Gen-ID 8036
Isotype IgG
Western blot Yes
ImmunoKjemi Yes
ImmunoFluorescens Yes
Modifikasjon Unmodified
Epitop 36-120/582
Immunogen KLH conjugated synthetic peptide derived from human SHOC2/Sur8
Skjema Liquid
Molekylvekt 65 kDa
Rensing Purified by Protein A
Konsentrasjon 1 µg/µl
Lagringsbuffer Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Lagringstemp Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Frakttemp. 4 °C
Uttestet applikasjon ICC

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