Anti-SHOC2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Leverandør: Bioss
BS-7934R-FITC
BOSSBS-7934R-FITCEA 10450 NOK
BOSSBS-7934R-FITC
Anti-SHOC2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
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Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. AffectedMore Product Information
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