Anti-Factor 12 heavy chain Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Leverandør: Bioss
BS-9503R-A680
BOSSBS-9503R-A680EA 10450 NOK
BOSSBS-9503R-A680
Anti-Factor 12 heavy chain Rabbit Polyclonal Antibody (Alexa Fluor® 680)
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This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factorMore Product Information
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