Anti-TrpV1 Mouse Monoclonal Antibody [clone: BS397]

Leverandør: Biosensis
M-1714-100
BSENM-1714-100EA 3675 NOK
BSENM-1714-100
Anti-TrpV1 Mouse Monoclonal Antibody [clone: BS397]
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The capsaicin receptor (VR1, TRPV1) is a ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. The receptor seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. It is involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- andMore Product Information
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