Anti-Bim/BOD Rabbit Polyclonal Antibody

Leverandør: ENZO LIFE SCIENCES
ADIAAP330E
ENZOADIAAP330EEA 5775 NOK
ENZOADIAAP330E
Anti-Bim/BOD Rabbit Polyclonal Antibody
Antistoffer
Bim is a critical regulator of lymphocyte homeostasis, acts as a barrier against autoimmune disease and is necessary for the apoptotic response to certain stress signals.

  • Dilution Range: 20 µg/ml for Immunohistochemistry, 1 µg/ml, colorimetric for Western blot
  • Detects a band of ~23 kDa by Western blot

All isoforms of Bim contain the C-terminal Bcl-2 homology domain known as BH3. Certain apoptotic stimuli release Bim from the complex which allows it to translocate to the mitochondria and bind to Bcl-2 or its homologues, thereby promoting apoptosis.

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SPESIFIKASJONER

Antigensymbol Bim/BOD
Environmentally Preferable
Antistofftype Primary
Klonalitet Polyclonal
Konjugering Unconjugated
Reaktivitet Human,Rat,Mouse
Vert Rabbit
Isotype
Western blot Yes
ImmunoKjemi Yes
Immunogen Synthetic peptide corresponding to the sequence near the middle of human Bim/BOD
Skjema Liquid
Rensing Purified by peptide affinity chromatography
Lagringsbuffer PBS containing 0,02% sodium azide
Lagringstemp 4 °C
Frakttemp. Blue ice not frozen

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