Anti-TRAIL-R4 Rabbit Polyclonal Antibody

Leverandør: ENZO LIFE SCIENCES
ADIAAP371E
ENZOADIAAP371EEA 5600 NOK
ENZOADIAAP371E
Anti-TRAIL-R4 Rabbit Polyclonal Antibody
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TRAIL decoy receptors (DcR1, DcR2, and osteoprotegerin/OPG) completely or partially lack the signaling death domain, and/or are secreted from cells and unable to transmit intracellular signals.

  • Dilution range: 10 µg/ml for Immunocytochemistry, 1:1,000 to 1:2,000 for Western blot
  • Detects a band of ~36 kDa by Western blot

Expression of DcRs promotes survival by sequestration of apoptotic ligands. A fourth identified decoy receptor, DcR3, binds both FasL and the vascular endothelial cell growth inhibitor (VEGI), inhibiting Fas and DR3 death signals.

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