Human Recombinant Bc1-w (from E. coli)

Leverandør: ProSci Inc.

91-088
PRSI91-088EA 7225 NOK
PRSI91-088
Human Recombinant Bc1-w (from E. coli)
Proteiner

Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.


  • Fusion-Tag: C-6 His tag


This recombinant protein can be used for biological assays.


NB: For research use only.

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