Human recombinant Autophagy 4C (from E. coli)

Leverandør: ProSci Inc.

92-044
PRSI92-044EA 10875 NOK
PRSI92-044
Human recombinant Autophagy 4C (from E. coli)
Proteiner

Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.


  • This recombinant protein can be used for biological assays. For research use only.


Fusion-Tag: C-6 His tag

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SPESIFIKASJONER

Protein/peptide name Autophagy 4C
Environmentally Preferable
Protein synonyms AUTL3|Cysteine Protease ATG4C|AUTL1|AUT-like 3 Cysteine Endopeptidase|APG4C|ATG4C|Autophagy-Related Protein 4 homolog C|Autophagy-Related Cysteine Endopeptidase 3|Autophagin-3
Protein/peptide type Recombinant
Arter Human
Kilde E. coli
Sekvens Met1-Leu458
Renhet > 95% as determined by reducing SDS-PAGE
Formulering Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molekylvekt 53.56 kD
Lagringsforhold Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Tag sekvens C-6 His tag
Uttestet applikasjon Bioassay

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