Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Leverandør: STEMCELL Technologies

100-0899
STMC100-0899EA 0 NOK
STMC100-0899
Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)
Proteiner

Human amyloid-β (1 to 42) peptide is a neurotoxic peptide fragment that can oligomerize to form amyloid plaques, thus contributing to the onset of Alzheimer's disease (Paradis et al.; Teplow; Wolfe). These neurotoxic peptide fragments also modulate the expression of Bcl-2 and Bax in human neurons (Paradis et al.).


NOTE: Human Amyloid-β (1-42) Peptide oligomers and fibrils are considered neurotoxic. Please contact your workplace safety committee for guidance before planning any work using Human Amyloid-β (1-42) Peptide. DISEASE MODELING · Induces neuronal death in human neurons in vitro and in vivo (Paradis et al.). Increases production of TNF-α in rat astrocytes (Hughes et al.).


NB: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

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