Anti-HIF1A Mouse Monoclonal Antibody (CF405S) [clone: HIF1A-84]

Leverandør: Biotium
BNC040084-500 BNC040084-100
BNC040084-500EA 6875 NOK
BNC040084-500 BNC040084-100
Anti-HIF1A Mouse Monoclonal Antibody (CF405S) [clone: HIF1A-84]
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HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to aMore Product Information
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