Microcystin-YR, Enzo Life Sciences

Leverandør: ENZO LIFE SCIENCES

ALX350044C025 ALX350044C100
ENZOALX350044C025EA 3150 NOK
ENZOALX350044C025 ENZOALX350044C100
Microcystin-YR, Enzo Life Sciences
Proteiner

Inhibitor of PP1 and PP2A


Analog of microcystin-LR (Prod. No. ALX-350-012) with Tyr substituted in place of Leu. As for all microcystins the conjugated double bonds in the ADDA moiety cause a characteristic absorption maximum at 238 nm. The Tyr residue in position 2 of microcystin-YR confers an absorption maximum at 232 nm. Potent inhibitor of eukaryotic protein phosphatases 1 and 2 A. Useful as a reference compound in environmental analysis. The hydroxyl group of the Tyr residue may prove useful for linking microcystin-YR via conjugation to other chemicals. Inhibits the synthesis of proteases such as cathepsin D and L, and arginine aminopeptidase.


Isolated from Microcystis aeruginosa.

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