Human amyloid-beta (1-40) peptide

Leverandør: Cayman Chemical

21617-1 21617-500
CAYM21617-1EA 7875 NOK
CAYM21617-1 CAYM21617-500
Human amyloid-beta (1-40) peptide
Proteiner

Amyloid-β (1-40) peptide Aβ (1-40) is a 40-residue protein fragment of the C-terminal portion of the β-amyloid protein implicated in Alzheimer’s disease. Aβ (1-40) is more abundant, less neurotoxic, and does not form oligomers as easily as amyloid-β (1-42) peptide (Aβ (1-42).


  • More abundant
  • Less neurotoxic
  • Does not form oligomers as easily as amyloid-β (1-42) peptide (Aβ (1-42)


In rat cortical cultures, Aβ (1-40) (3 µM) prevented neuronal cell death by inhibiting fibril formation when administered concurrently with Aβ (1-42) (5, 10, and 20 µM). In the same study, Aβ (1-40) prevented neuronal damage when injected into rat entorhinal cortex with Aβ (1-42) (both at 400 µM).


NB: This product is not for human or veterinary use.

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SPESIFIKASJONER

Protein/peptide name Amyloid-beta (1-40) Peptide
Protein synonyms Aβ (1-40)
Environmentally Preferable
Arter Human
Kilde
CAS-nr 131438-79-4
Renhet >95%
Formulering Crystalline solid
Molekylvekt 4329,9 g/mol
Molekylformel C₁₉₄H₂₉₅N₅₃O₅₈S
Lagringsforhold –20 °C

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