N,O-Bis(trimetylsilyl)acetamid silylation reagent, for GC derivatisation

Leverandør: MACHEREY-NAGEL
Danger

Synonymer: BSA, Silyl Derivatisation, Trimethylsilyl N-(trimethylsilyl)acetimidate, Trimethylsilyl N-trimethylsilylacetamidate

701210.110 701210.150 701210.510
MANA701210.110EA 1025 NOK
MANA701210.110 MANA701210.150 MANA701210.510
N,O-Bis(trimetylsilyl)acetamid silylation reagent, for GC derivatisation
N,O-Bis(trimetylsilyl)acetamid

BSA is a strong silylation reagent that forms very stable TMS derivatives with a large variety of compounds, e.g., non-sterically hindered alcohols, carboxylic acids, phenols, enols, steroids, (biogenic) amines and alkaloids.


  • Silylation can be applied on many compounds
  • Silylation reagents are easily prepared
  • BSA derivatives have great volatility


Not recommended for use with carbohydrates or very low molecular weight compounds. Good solvent for polar compounds, but frequently used in combination with a solvent (pyridine, DMF etc.) or with other silylation reagents or catalysts such as TFA, HCl or TMBS. Used in combination with DMF, BSA is the reagent of choice for derivatizing phenols.

Formel: C₈H₂₁NOSi₂
MW: 203,43 g/mol
Kokepunkt: 71–73 °C (35 mm Hg)
Tetthet: 0,832 g/cm³ (d20°/4°)
MDL nummer: MFCD00008270
CAS-nummer: 10416-59-8
FN: 3316
ADR: 9,II

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