BI-D1870 ≥98% (by HPLC)

Leverandør: ENZO LIFE SCIENCES

Synonymer: 2-((3,5-Difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one

BMLEI4070001 BMLEI4070005
ENZOBMLEI4070001EA 710 NOK
ENZOBMLEI4070001 ENZOBMLEI4070005
BI-D1870 ≥98% (by HPLC)
BI-D1870

S6 kinase inhibitor


Cell permeable, ATP-competitive inhibitor of the four isoforms of ribosomal S6 kinase (p90 RSK) (IC50's at 100µM ATP: RSK1 = 31nM, RSK2 = 24nM, RSK3 = 18nM, RSK4 = 15nM). Does not significantly inhibit 10 other AGC kinases, and over 40 other protein kinases at 100X concentrations. Acts on the N-terminal AGC kinase domain. Completely prevents PMA-induced TSC2 phosphorylation.

Formel: C₁₉H₂₃F₂N₅O₂
MW: 391,423 g/mol
MDL nummer: MFCD11223662
CAS-nummer: 501437-28-1

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