Tyrphostin AG-126 ≥98% (by HPLC)

Leverandør: ENZO LIFE SCIENCES

BMLEI2630005 BMLEI2630025
ENZOBMLEI2630005EA 1300 NOK
ENZOBMLEI2630005 ENZOBMLEI2630025
Tyrphostin AG-126 ≥98% (by HPLC)
Tyrphostin AG-126

AG-126 prevents lipopolysaccharide-induced lethal toxicity (septic shock) in mice. Administered at 1.5 mg/mouse, it reduced LPS-induced lethal toxicity from 95% to 10%. AG-126 greatly reduces LPS-induced tyrosine phosphorylation of p42MAPK in murine peritoneal macrophages at 50 µM. EGFR, Her-2/neu receptor or PDGF-R are not inhibited at 100 µM. Inhibits tyrosine kinase-dependent B cell receptor signaling.


  • Inhibits tyrosine kinase-dependent B cell receptor signaling


Yellow solid.


Soluble in DMSO (25mg/ml) or 100% ethanol (5mg/ml warm).

Formel: C₁₀H₅N₃O₃
Lagringstemperatur: Romtemperatur
MDL nummer: MFCD00236448
CAS-nummer: 118409-62-4
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=6298223c475925f46712741e5195d64fe4a6d9ae&vid=1b6917c92d32148a7c38d78a80f41be6cb0900ee&prid=web&clid=SAPDAM

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