3-Morpholinosydnonimine ≥98% (by HPLC)
Leverandør: ENZO LIFE SCIENCES
SIN-1 is a metabolite of molsidomine which decomposes spontaneously in solution in the presence of oxygen, releasing NO and superoxide anion under physiological conditions. Since NO and superoxide react to form peroxynitrite, SIN-1 may actually produce peroxynitrite under physiological conditions. It is a potent vasodilator and inhibitor of platelet aggregation and produces significant protective effects in myocardial ischemia-reperfusion. The effects of SIN-1 are markedly attenuated by nitroglycerin-induced tolerance. Inhibits cysteine proteases.
- Releases NO and superoxide anion under physiological conditions
White to off-white solid.
Soluble in water (25mg/ml), 100% ethanol or DMSO (>5mg/ml).
Formel:
C₆H₁₀N₄O₂·HCl Smeltepunkt: 186…187 °C Lagringstemperatur: Fryseskap |
CAS-nummer:
33876-97-0 |
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