Alsterpaullone ≥95%
Leverandør: ENZO LIFE SCIENCES
Synonymer:
7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one
ALX270275M005
ENZOALX270275M005EA
6400
NOK
ENZOALX270275M005
Alsterpaullone ≥95%
Alsterpaullone
Inhibitor of CDK and GSK
Potent inhibitor of CDK1/cyclin B (IC50=35nM). Potent and selective inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50=200nM), CDK5/p25 (IC50=40nM), CDK5/p35 (IC50=40nM) and GSK-3β . Induces apoptosis by activation of caspase-8 and caspase-9 followed by disruption of the mitochondrial potential.Licensed from NCI.
Formel:
C₁₆H₁₁N₃O₃ MW: 293,3 g/mol |
MDL nummer:
MFCD02683579 CAS-nummer: 237430-03-4 |
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