Anti-CD90 (Thy-1) Mouse Monoclonal Antibody [clone: 5E10] (PerCP-Cy5.5)

Leverandør: STEMCELL Technologies
60045PS 60045PS.1
STMC60045PSEA 0 NOK
STMC60045PS STMC60045PS.1
Anti-CD90 (Thy-1) Mouse Monoclonal Antibody [clone: 5E10] (PerCP-Cy5.5)
Antistoffer
Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD90 (Thy-1), PerCP-Cy5.5-conjugated.

  • Hematopoietic stem
  • Progenitor cells
  • Mammary cells
  • Mesenchymal stem
  • Progenitor cells

The 5E10 antibody reacts with CD90 (Thy-1), a GPI-linked membrane glycoprotein that is N-glycosylated at two sites, giving rise to 25 - 37 kDa molecules. CD90 has roles in signal transduction, cell adhesion and migration, neurite outgrowth, T cell activation, tumor suppression, and inhibition of the proliferation and differentiation of hematopoietic stem cells. It is a known ligand of β2 and β3 integrins and upregulates synthesis of fibronectin, osteonectin and thrombospondin. CD90 is broadly expressed, being found on human thymocytes, neurons, some glial cells, fibroblasts, activated endothelial cells, some leukemia cell lines and a distinct subset (<1%) of CD3+CD4+ T cells in human peripheral blood. CD90 is also expressed by small subsets of CD34+ cells in fetal liver, umbilical cord blood, bone marrow and mobilized peripheral blood cells. CD90 is considered an important marker for hematopoietic stem and progenitor cells and, in combination with other markers such as CD34, is useful to identify and isolate these cells by FACS. This antibody clone has been verified for labeling human mesenchymal cells grown in MesenCult™ Proliferation Kit (Human; Catalog #05411) and MesenCult™-XF Medium (Catalog #05420).

NB: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD90 (Thy-1)
Clonality: Monoclonal
Clone: 5E10
Conjugation: PerCP-Cy5.5
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Baboon, Cynomolgus monkey, Dog, Human, Macaque, Pig, Rhesus monkey
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