Human Recombinant IL-1alpha (Animal Free) (from E. coli)

Supplier: Shenandoah Biotechnology

100-173AF-100U 100-173AF-10UG 100-173AF-1MG 100-173AF-500U
SHBT100-173AF-100UEA 9050 NOK
SHBT100-173AF-100U SHBT100-173AF-10UG SHBT100-173AF-1MG SHBT100-173AF-500U
Human Recombinant IL-1alpha (Animal Free) (from E. coli)
Proteins and Peptides

Interleukin 1 alpha (IL-1α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1α signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1α and the independently regulated IL-1β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.


  • High Quality
  • Low Endotoxin
  • Affordable


A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.  This product is for research use only and is not for use in humans.  


Caution: For research use only.

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SPECIFICATIONS

Protein/peptide name IL-1alpha/IL-1F1
Environmentally Preferable
Protein synonyms IL-1F1|LAF|LEM|FAF|BAF
Protein/peptide type Recombinant
Protein function Cytokine
Species Human
Source E. coli
Conjugation Unconjugated
Gene ID P01583
Sequence SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
Protease-free N
Animal-free Y
Nuclease-free N
Carrier-free Y
Endotoxin-free N
Endotoxin level Low
Endotoxin content Endotoxin LAL (EU/µg) ≤1
Biological activity Bioactivity assay: D10,G4,1 cell proliferation, ED50 ≤0,05 ng/ml, Bioactivity ≥2,0×10⁷ units/mg
Purity ≥95%
Grade RUO
Formulation 10 mM sodium phosphate, pH 7,5
Molecular weight 18 kDa
Reconstitution instructions Sterile water at 0.1 mg/ml
Storage conditions –20 °C
Shipping temperature RT
Tested applications Bioassay

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