Human Recombinant SDF-1 B/CXCL12 (from E. coli)

Leverandør: Shenandoah Biotechnology

800-09-100UG 800-09-10UG 800-09-1MG 800-09-500UG
SHBT800-09-100UGEA 0 NOK
SHBT800-09-100UG SHBT800-09-10UG SHBT800-09-1MG SHBT800-09-500UG
Human Recombinant SDF-1 B/CXCL12 (from E. coli)
Proteiner

Cytokines for the differentation of human monycyte-derived dendritic cells. Dendritic cells are an important type of immune cell that function to activate T and B cells via their role as an antigen presenting cell. Monocytes isolated from peripheral blood can be differentiated to immature dendritic cells (iDCs) through culturing in the presence of interleukin-4 (IL-4) and granulocyte-macrophage colony stimulating factor (GM-CSF).


  • High quality
  • Low endotoxin
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The characteristics of monocyte-derived iDCs are detectable after culture with IL-4/GM-CSF and include: the down regulation of CD14 surface expression, an increase in dextran uptake and an increased response to MIP-1α. Subsequent culturing with pro-inflammatory cytokines (such as TNF-α, IL-1β, and IL-6) can further differentiate the iDCs into mature dendritic cells (mDCs) that have full T cell stimulating capacity. This bundle includes 1x 100 μg of Recombinant Human IL-4 and 1x 100 μg of Recombinant Human GM-CSF.


NB: For research use only.

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