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Rapamycin ≥98.0% (by HPLC)

Artikkenummer: (TCIAR0097-25MG)

Produsent: TCI

Beskrivelse: Rapamycin ≥98.0% (by HPLC)

UOM: 1 * 25 mg

Sertifikater Tilbud

N/A Each

Beskrivelse: Macrocyclic-triene antibiotic possessing potent immunosuppressant activity. It forms a complex with FKBP12 that binds to an effector, thus inhibiting IL-2 and other growth promoting lymphokines. The effectors were identified as FRAP (FKBP12 rapamycin-associated protein) and RAFT1 (rapamycin and KFBP12 target). Rapamycin/FKBP complex does not inhibit FRAP PI 4-kinase activity, but does inhibit FRAP autophosphorylation. Rapamycin induces inhibition of p70s6k, p33cdk2 and p34cdc2. Selectively blocks signaling leading to the activation of p70/85 S6 kinase. Enhances apoptosis. Activator of autophagy both in vitro and in vivo.

Rapamycin ≥99%

Produsent: Thermo Fisher Scientific

Beskrivelse: Rapamycin ≥99%

HMS Sertifikater

Rapamycin (from Streptomyces hygroscopicus)

Produsent: Apollo Scientific

Beskrivelse: Macrocyclic triene antibiotic.

Rapamycin ≥98%, pulver

Produsent: MP Biomedicals

Beskrivelse: Rapamycin binds to and inhibits the molecular target of rapamycin (mTOR). It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). Rapamycin is a potent immunosuppressant and has anticancer activity.