Du søkte etter: 8-(4-Chlorophenylthio)guanosine+3\',5\'-cyclic+Monophosphothioate

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.

New Product

Artikkenummer: (ENZOBMLCN2060001)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS

UOM: 1 * 1 mg

New Product Tilbud

Artikkenummer: (ENZOALX480072M001)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Inhibitor of cGMP-dependent protein kinase (PKG) 1α (cGMP antagonist). Resistant against mammalian cyclic nucleotid-dependent phosphodiesterases. No metabolic side effects. Low membrane permeability.

UOM: 1 * 1 mg

New Product Tilbud

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Selective activator of cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II as well as of cGMP-gated ion channels.

New Product

Artikkenummer: (ENZOALX480031M005)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Activator of PKG and CNG channels.

UOM: 1 * 5 mg

New Product Tilbud

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.

New Product

Artikkenummer: (ENZOALX480025M001)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: PKA activator.

UOM: 1 * 1 mg

New Product Tilbud

Artikkenummer: (ENZOALX480085M001)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).

UOM: 1 * 1 mg

New Product Tilbud

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Specific, potent and membrane permeant activator of the Epac cAMP receptor.

New Product

Produsent: ENZO LIFE SCIENCES

Beskrivelse: PKA activator.

New Product

Produsent: Cayman Chemical

Beskrivelse: 3'3'-cGAMP (sodium salt) ≥98%

Artikkenummer: (BOSSBS-13470R-CY5)

Produsent: Bioss

Beskrivelse: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

UOM: 1 * 100 µl

Tilbud

Artikkenummer: (BOSSBS-3892R-CY5)

Produsent: Bioss

Beskrivelse: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).

UOM: 1 * 100 µl

Tilbud

Artikkenummer: (BOSSBS-13470R-CY3)

Produsent: Bioss

Beskrivelse: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

UOM: 1 * 100 µl

Tilbud

Artikkenummer: (BOSSBS-3892R-A680)

Produsent: Bioss

Beskrivelse: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).

UOM: 1 * 100 µl

Tilbud

Artikkenummer: (BOSSBS-13470R-A488)

Produsent: Bioss

Beskrivelse: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

UOM: 1 * 100 µl

Tilbud