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Human recombinant UBE2G2 (from E. coli)

Artikkenummer: (PRSI91-976)

Produsent: ProSci Inc.

Beskrivelse: Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to the ubiquitin-conjugating enzyme family. It shares 60% and 100% sequence identity with S.cerevisiae Ubc7 and mouse respectively. The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins. The mechanism of K48-linked poly-ubiquitination by UBE2G2/GP78 appears to involve the transfer of preassembled Ub chains from UBE2G2 to lysine residues in a substrate. The E2 and E3 enzymes form a large hetero-oligomer which brings multiple UBE2G2 molecules into close proximity which allows for Ub transfer between neighboring E2s.

UOM: 1 * 1 Each

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N/A Each

2-Bromethylamine hydrobromide for syntese, Sigma-Aldrich®

Produsent: Merck

Beskrivelse: 2-Bromethylamine hydrobromide for syntese, Sigma-Aldrich®

HMS

Roller bottles, Nunc™ InVitro™

Artikkenummer: (734-2394)

Produsent: Thermo Fisher Scientific

Beskrivelse: PETG, sterile.

UOM: 1 * 20 Items

Tilbud

N/A Each

Biotin ethylenediamine hydrobromide ≥95% (by TLC), Sigma-Aldrich®

Artikkenummer: (B9181-25MG)

Produsent: SIGMA ALDRICH MICROSCOPY

Beskrivelse: Biotin ethylenediamine hydrobromide. ≥95% (TLC), solid ((3aS,4S,6aR)-N-(2-Aminoethyl)hexahydro- 2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; N-(2-Aminoethyl)biotinamide hydrobromide)

UOM: 1 * 25 mg

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