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Malonyl coenzyme A lithium salt ≥90%

Produsent: Cayman Chemical
Beskrivelse: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

Image Unavailable-07441-10MG

Supelco® Organic Reference Standard, Malonyl-L-Carnitine Lithium Salt

Produsent: Merck
Beskrivelse: Organic Standard, Malonyl-ʟ-carnitine lithium salt

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Cerulenin ≥98%, crystalline solid

Produsent: Cayman Chemical
Beskrivelse: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Image Unavailable-BOSSBS-12952R-A680

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikkenummer: (BOSSBS-12952R-A680)
Produsent: Bioss
Beskrivelse: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A680

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikkenummer: (BOSSBS-12954R-A680)
Produsent: Bioss
Beskrivelse: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A750

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Artikkenummer: (BOSSBS-12954R-A750)
Produsent: Bioss
Beskrivelse: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12952R-A750

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikkenummer: (BOSSBS-12952R-A750)
Produsent: Bioss
Beskrivelse: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-APOSBIC7401-100MG

Coenzyme A trilithium salt

Produsent: Apollo Scientific
Beskrivelse: Coenzyme A trilithium salt

Image Unavailable-CAYM10547-5

4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Produsent: Cayman Chemical
Beskrivelse: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Image Unavailable-CAYM21722-10

Coenzyme A sodium salt hydrate ≥95%

Produsent: Cayman Chemical
Beskrivelse: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

Image Unavailable-8.22084.0250

L(+)-Lithium lactate for syntese, Sigma-Aldrich®

Produsent: Merck
Beskrivelse: L(+)-Lithium lactate for syntese, Sigma-Aldrich®

HMS

Image Unavailable-19533-5MG

Supelco® Organic Reference Standard, Geranyl Pyrophosphate Lithium Salt

Artikkenummer: (19533-5MG)
Produsent: Merck
Beskrivelse: Organic Standard, Geranyl pyrophosphate lithium salt
UOM: 1 * 5 mg
Image Unavailable-CAYM18167-25

Riboflavin 5'-monophosphate sodium salt hydrate

Produsent: Cayman Chemical
Beskrivelse: Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalysing oxidation and reduction reactions in a variety of biosynthetic pathways.

Sertifikater

Image Unavailable-73885-10MG

Supelco® Organic Reference Standard, D-2-Phosphoglyceric Acid Lithium Salt

Produsent: Merck
Beskrivelse: Organic Standard, ᴅ-2-Phosphoglyceric acid lithium salt

Image Unavailable-55385-10MG

Supelco® Organic Reference Standard, 3-Phosphoshikimic acid lithium salt

Artikkenummer: (55385-10MG)
Produsent: Merck
Beskrivelse: Organic Standard, 3-Phosphoshikimic acid lithium salt
UOM: 1 * 10 mg
Image Unavailable-89163-1MG

Supelco® Organic Reference Standard, (±)-Mevalonic acid-(methyl-d₃) lithium salt

Artikkenummer: (89163-1MG)
Produsent: Merck
Beskrivelse: Organic Standard, (±)-Mevalonic acid-(methyl-d₃) lithium salt
UOM: 1 * 1 mg
Pris på forespørsel
Lager for dette produktet er begrenset, men kan være tilgjengelig i en lagerbygning i nærheten av deg. Vennligst sørg for at du er logget inn på nettstedet, slik at tilgjengelige lager kan vises. Hvis call er fortsatt vises og du trenger hjelp, kan du ringe oss på 1-800-932 - 5000.
Lager for dette punktet er begrenset, men kan være tilgjengelig i en lagerbygning i nærheten av deg. Vennligst sørg for at du er logget inn på nettstedet, slik at tilgjengelige lager kan vises. Hvis call er fortsatt vises og du trenger hjelp, kan du ringe oss på 1-800-932 - 5000.
NB Dette produkt er regulert i henhold til norsk lov.
Dersom ytterligere informasjon er nødvendig fra deg vil du bli kontaktet av VWR via e-post.
OBS! Etanol er underlagt bestemmelse om særavgift, jfr LOV-1993-05-19-11-§1. VWR selger kun etanol til kunder som kan fremlegge avgiftsfritak for udenaturert etanol, jfr. § 3-3-7 ( forskrifter om særavgifter).
NB Dette produkt er regulert i henhold til norsk lov.
Dersom ytterligere informasjon er nødvendig fra deg vil du bli kontaktet av VWR via e-post.
OBS! Etanol er underlagt bestemmelse om særavgift, jfr LOV-1993-05-19-11-§1. VWR selger kun etanol til kunder som kan fremlegge avgiftsfritak for udenaturert etanol, jfr. § 3-3-7 ( forskrifter om særavgifter).
Dette produktet har blitt blokkert for din organisasjon. Ta kontakt med din innkjøpsavdeling for mer informasjon.
Det opprinnelige produktet er ikke lenger tilgjengelig. Varen som vises er tilgjengelig.
Produkt (er) merket med dette symbolet er ikke lenger tilgjengelig og selges til lageret er tomt. Alternativer kan være tilgjengelige ved å søke med VWR Katalognummer ovenfor. Hvis du trenger ytterligere hjelp, ring VWR kundeservice 22900000
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