Du søkte etter: Antistoffer

Artikkenummer: (ENZOADISPA240J)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: GrpE (Glucose Regulated Protein E. coli) is encoded by a monocistronic E. coli gene, which is under the control of both s32 and s70 transcription factors. The GrpE protein is a so-called co-chaperone because it is known to assist the DnaK (Hsp70) protein to effectively carry out DnaK-dependent chaperone activity (i.e. protein folding, protein transport, disaggregation of heat inactivated proteins, activation of mutant protein).

UOM: 1 * 1 mg

New Product Tilbud

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Recommended Applications: IP, WB

Species reactivity:

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Artikkenummer: (ENZOENZABS2500100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Recommended Applications: IF

Species reactivity: Human, Dog

UOM: 1 * 1 Each

New Product Tilbud

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Recommended Applications: ELISA, IHC, WB

Species reactivity: Human

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Artikkenummer: (ENZOENZABS1850100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Recommended Applications: IF, IHC (FS)

Species reactivity: Human, Sheep

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (ENZOENZABS2250100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Recommended Applications: Flow Cytometry, WB

Species reactivity: Human

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (ENZOENZABS2420100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Recommended Applications: Flow Cytometry, IHC (FS), Internalization

Species reactivity: Human, Dog

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (ENZOALX804527C100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Host: Rat, Isotype: IgG2a

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (ENZOALX804528C100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Host: Rat, Isotype: IgG2a

UOM: 1 * 1 Each

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Artikkenummer: (ENZOALX804837C100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Host: Mouse, Isotype: IgG1

UOM: 1 * 1 Each

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Artikkenummer: (ENZOALX804805C100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.

UOM: 1 * 1 Each

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Artikkenummer: (ENZOALX804804C100)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Host: Rat, Isotype: IgG2a

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (ENZOADIAAP149E)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

UOM: 1 * 1 Each

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development. Agrin, MuSK, and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation.

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction. Agrin, MuSK and Rapsyn are all essential components for AChR aggregation through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface, and induces AChR aggregation. The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin. The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components. This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites, increasing the predicted MW from 200kDa to ~600kDa. The diagram shown indicates the domain structure and functional regions of agrin, as well as domains required for AChR aggregation and alpha-dystroglycan and heparin binding.  Various agrin isoforms are generated by alternative splicing at the X, Y and Z sites, and differ in the presence or absence of small inserts. The isoforms can determine the biological activity of agrin and their expression in specific tissues and stages of development. While no difference in functional activity has been detected between splicing variants at site X, insertion of a 4 aa peptide at site Y modestly increases agrins nAChR clustering activity. Insertion of an 8 aa peptide at splicing site Z increases the clustering activity of soluble rat agrin 10,000 fold.

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development.

New Product