Du søkte etter: Chiral+Technologies

Artikkenummer: (736-0198)

Produsent: THERMO MATRIX TECHNOLOGIES

Beskrivelse: PP. The square well geometry of this 96-well plate makes it ideal for bacterial growth applications.

UOM: 1 * 50 Items

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Produsent: BW TECHNOLOGIES

Beskrivelse: Single gas detectors for safety and compliance in harsh environments with extreme temperatures.

Artikkenummer: (STMC07820)

Produsent: STEMCELL Technologies

Beskrivelse: Density gradient medium for the isolation of viruses, organelles, macromolecules, or cells.

UOM: 1 * 250 mL

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Artikkenummer: (STMC10955)

Produsent: STEMCELL Technologies

Beskrivelse: Supplement for the differentiation of mouse naïve CD4+ T cells into Th2 cells.

UOM: 1 * 1 mL

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Artikkenummer: (STMC10973)

Produsent: STEMCELL Technologies

Beskrivelse: Culture supplement for the differentiation of human naïve CD4+ T cells into Th1 cells.

UOM: 1 * 1 mL

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Artikkenummer: (STMC36253)

Produsent: STEMCELL Technologies

Beskrivelse: Dulbecco's Modified Eagle's Medium (DMEM) with 1000 mg/L D-glucose.

UOM: 1 * 500 mL

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Produsent: THERMO MATRIX TECHNOLOGIES

Beskrivelse: D.A.R.T’S™ (Disposable Automation Research Tips) have been designed for the ultimate performance in automated pipetting.

Produsent: BW TECHNOLOGIES

Beskrivelse: Accessory for gas detection, For: Extreme, Replacement sensor screens with gasket

Produsent: STEMCELL Technologies

Beskrivelse: Receptor activator of nuclear factor kappa-B ligand (RANKL) is a member of the tumor necrosis factor (TNF) superfamily (Anderson <i>et al.</i>). Cytokines in the TNF superfamily are involved in a variety of long-term cellular activities such as differentiation, proliferation, and cell death (MacEwan). RANKL is a type II homotrimeric transmembrane protein expressed in both a membrane-bound and secreted form (Ikeda <i>et al.</i>). RANKL binds to the receptor activator of nuclear factor kappa-B (RANK). Upon binding to its receptor, RANKL activates the AKT signaling pathway (Moon <i>et al.</i>). Osteoprotegerin (OPG) may also bind RANKL, and this binding competes with RANKL-RANK binding (Lacey <i>et al.</i>). RANKL is involved in osteoclastogenesis (Lacey <i>et al.</i>; Yasuda <i>et al.</i>) and T cell activation (Wong <i>et al.</i>).

Produsent: STEMCELL Technologies

Beskrivelse: Interleukin 13 (IL-13) is a cytokine important in type 2 immune responses and is expressed by T helper type 2 (Th2) cells and group 2 innate lymphoid cells (ILC2s) (Pulendran and Artis). IL-13 binds a receptor composed of IL-4Ra and IL-13Ra1 or IL-13Ra2 (Wynn 2003). IL-13 receptor is expressed on B cells and promotes B cell proliferation, induces class switching to IgG4 and IgE, and functions in the recruitment and activation of IgE-producing B cells (Hershey). The receptor is also expressed on basophils, eosinophils, mast cells, endothelial cells, fibroblasts, monocytes, macrophages, respiratory epithelial cells, and smooth muscle cells (Hershey). Signaling through the IL-13 receptor activates the JAK/STAT and IRS-1/IRS-2 pathways. <i>in vivo</i>, IL-13 has a role in resistance to extracellular helminth parasites by regulating gastrointestinal parasite expulsion, as well as in airway hyperresponsiveness, allergic inflammation, tissue remodeling, tumor cell growth, and fibrosis (Wynn 2015). Secreted IL-13 is a protein consisting of 112 amino acids with a molecular mass of 10 kDa (Hershey). Human IL-13 is not species-specific but has greater activity on human cells compared to mouse cells (Hershey).

Artikkenummer: (STMC75002)

Produsent: STEMCELL Technologies

Beskrivelse: Propidium Iodide (PI) is a red-fluorescent cell viability dye which is excluded from live cells with intact membranes, but penetrates dead or damaged cells and binds to DNA and RNA by intercalating between the bases.

UOM: 1 * 10 mg

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Produsent: STEMCELL Technologies

Beskrivelse: Fibroblast growth factor 18 (FGF-18) is a growth factor and member of the FGF subfamily. FGF-18 is most similar to FGF-8 and FGF-17, and is secreted in adult lung and developing tissues (Ohbayashi <i>et al.</i>). FGF-18 signals through FGF receptor 3 (FGFR3) to regulate proliferation, differentiation, and matrix production of articular and growth plate chondrocytes <i>in vivo</i> and in vitro (Davidson <i>et al.</i>). FGF-18 has skeletal functions and protects articular cartilage by gene expression profiling and regulates proliferation and differentiation of midline cerebellar structures (Mori <i>et al.</i>). Also, recombinant human FGF-18 has been shown to effectively regulate hair growth (Song <i>et al.</i>).

Produsent: STEMCELL Technologies

Beskrivelse: Platelet-derived growth factor (PDGF) is a dimeric glycoprotein consisting of two disulfide bridge stabilized polypeptide chains, A and B, which are assembled as heterodimers (PDGF-AB) or homodimers (PDGF-AA and PDGF-BB) (Fretto <i>et al.</i>; Westermark and Heldin). PDGF signals through the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src and PI3K/AKT (Kim <i>et al.</i>). PDGF is a potent mitogen for cells of mesenchymal origin- like fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto <i>et al.</i>; Sachinidis <i>et al.</i>). PDGF-BB is secreted by osteoblasts to induce mesenchymal stem cell migration and angiogenesis. It has also been shown that PDGF-BB is secreted by preosteoclasts during bone modeling and remodeling to induce angiogenesis and thus proper osteogenesis (Xie <i>et al.</i>).

Produsent: STEMCELL Technologies

Beskrivelse: Complete kit for optimisation of genome editing in human cells.

Artikkenummer: (STMC100-1282)

Produsent: STEMCELL Technologies

Beskrivelse: Supplement (50X) without vitamin A for the culture of neural progenitor cells.

UOM: 1 * 100 mL

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Artikkenummer: (STMC100-1388)

Produsent: STEMCELL Technologies

Beskrivelse: Stimulating T cells with EBV (LMP1) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. EBV (LMP1) Peptide pool is a lyophilised mixture of 94 peptides from latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV; strain B95-8), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 386 on LMP1. LMP1 is essential for EBV-mediated growth transformation of B cells (Kaye <i>et al.</i>) and has been shown to downregulate toll-like receptor 9 (TLR9) expression in infected cells, a mechanism the virus may use to escape host innate immune recognition (Fathallah <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.

UOM: 1 * 1 AE

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