Du søkte etter: ENZO LIFE SCIENCES

Artikkenummer: (ENZOADI900092)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: For the quantitative determination of 11-dehydro-TXB2 in culture supernatants and urine from any species. Cited samples include serum.

UOM: 1 * 1 Each

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: TrkA inhibitor

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Beskrivelse: Akt inhibitor

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Beskrivelse: IKK inhibitor

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Artikkenummer: (ENZOBMLEI3710010)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: A selective inhibitor of p38α (IC50 = 3.2 nm) and p38β (IC50 = 3.2 nm), but not p38γ (IC50 > 50 μm), ERK2, JNK1 or MAPKAP2. Lowers blood glucose and improves glucose homeostasis in nonobese diabetic mice. Enhances axonal regeneration in animals with nerve transection.

UOM: 1 * 10 mg

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Artikkenummer: (ENZOBMLEI3850001)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: VEGFR inhibitor

UOM: 1 * 1 mg

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Artikkenummer: (ENZOALX305006M001)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Semisynthetic (from GM1).

UOM: 1 * 1 mg

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Beskrivelse: trans-Ned-19

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Beskrivelse: Genistein

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Artikkenummer: (ENZOALX306011M025)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: PKC inhibitor

UOM: 1 * 25 mg

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Artikkenummer: (ENZOBMLNA1380020)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Na+ channel blocker, K+ channel activator

UOM: 1 * 20 mg

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: Kavain is one constituent of kava-kava, an herbal drug of the South Pacific islands, which displays anti-convulsive, anxiolytic, analgesic and muscle relaxing properties. Kavain inhibits voltage-dependent Na+ channels in rat CA1 hippocampal neurons. It displays protective effects in the MPTP mouse model of Parkinson's disease but potentiates NMDA toxicity in the developing hippocampus.

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Artikkenummer: (ENZOBMLNH1070010)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Histamine H₁ receptor antagonist. An antagonist of low affinity neurotensin receptors.

UOM: 1 * 10 mg

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Artikkenummer: (ENZOBMLNS1120050)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Potent and selective serotonin uptake inhibitor (Ki=5.4nM). Modifies gene expression profile in Alzheimer lymphocytes. Clinically useful antidepressant.

UOM: 1 * 50 mg

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Artikkenummer: (ENZOBMLNS5300050)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Serotonin receptor ligand

UOM: 1 * 50 mg

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: The 90 kDa molecular chaperone family includes 90 kDa heat shock protein Hsp90 and 94 kDa glucose-regulated protein grp94, both major molecular chaperones of the cytosol and the endoplasmic reticulum. Mammalian cells express inducible Hsp90 alpha and constitutive Hsp90 beta isoforms that are encoded by separate genes. The amino acid sequences of human and yeast Hsp90 alpha are 85% and 90% homologous to those of Hsp90 beta, respectively. All known members of the Hsp90 protein family are highly conserved, especially in the N-terminal and C-terminal regions containing independent chaperone sites with different substrate specificity. These ubiquitous and highly conserved proteins account for 1-2% of all cellular protein in most cells. Hsp90 functions as part of the cell's powerful network of chaperones to fight the deleterious consequences of protein unfolding caused by non-physiological conditions. In the absence of stress, however, Hsp90 provides a necessary component of such fundamental cellular processes as hormone signaling and cell cycle control by serving as a chaperone for many key signaling molecules including steroid receptors, cell cycle kinases involved in signal transduction, and p53. As many of these client proteins are known oncogenes, Hsp90 inhibitors such as 17-AAG, a geldanamycin analog, have been of benefit in the treatment of many cancers.

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