Du søkte etter: RG-13022

Artikkenummer: (BOSSBS-15502R)

Produsent: Bioss

Beskrivelse: RGS14 is a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

UOM: 1 * 100 µl

Tilbud

Artikkenummer: (ANTIA302667-96)

Produsent: ANTIBODIES.COM

Beskrivelse: Human PITX2/RGS ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human PITX2/RGS in serum, plasma, tissue homogenates, and other biological fluids.

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (BOSSBS-9851R-A680)

Produsent: Bioss

Beskrivelse: The formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs. This process is mediated by the survival of motor neuron (SMN) protein, and is enhanced by modification of specific arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs). sDMA modification of Sm proteins is catalysed by the methylosome, a complex comprised of the type II methyltransferase PRMT5 (also designated Jak-binding protein 1, JBP1), pICln, and two novel factors. PRMT5 binds the Sm proteins via their arginine- and glycine-rich (RG) domains, while pICln binds the Sm domains. pICln also acts as an inhibitor of SnRNP assembly by preventing specific interactions between Sm proteins required for the formation of the Sm core. pICln is a highly conserved, ubiquitously expressed protein that localizes primarily to the cytoplasm, and may play a role as a swelling-activated anion channel or a channel regulator in addition to its function in the methylosome. The gene encoding human pICln maps to chromosome 11q14.1.

UOM: 1 * 100 µl

Tilbud

Artikkenummer: (BOSSBS-9851R-A750)

Produsent: Bioss

Beskrivelse: The formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs. This process is mediated by the survival of motor neuron (SMN) protein, and is enhanced by modification of specific arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs). sDMA modification of Sm proteins is catalysed by the methylosome, a complex comprised of the type II methyltransferase PRMT5 (also designated Jak-binding protein 1, JBP1), pICln, and two novel factors. PRMT5 binds the Sm proteins via their arginine- and glycine-rich (RG) domains, while pICln binds the Sm domains. pICln also acts as an inhibitor of SnRNP assembly by preventing specific interactions between Sm proteins required for the formation of the Sm core. pICln is a highly conserved, ubiquitously expressed protein that localizes primarily to the cytoplasm, and may play a role as a swelling-activated anion channel or a channel regulator in addition to its function in the methylosome. The gene encoding human pICln maps to chromosome 11q14.1.

UOM: 1 * 100 µl

Tilbud

Artikkenummer: (ANTIA312882-96)

Produsent: ANTIBODIES.COM

Beskrivelse: Human PITX2/RGS ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human PITX2/RGS in serum, plasma, and other biological fluids.

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (ANTIA307302-100)

Produsent: ANTIBODIES.COM

Beskrivelse: Rabbit monoclonal [ARC56103] antibody to PITX2/RGS for WB with samples derived from Human.

UOM: 1 * 100 µl

New Product Tilbud

Artikkenummer: (ANTIA253222-100)

Produsent: ANTIBODIES.COM

Beskrivelse: Mouse monoclonal [RG/26] antibody to beta III Spectrin for ELISA, WB, IF and IHC-P with samples derived from Human, Mouse and Rat.

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (J64630.MA)

Produsent: Thermo Fisher Scientific

Beskrivelse: A cell-permeable, specific DNA methyltransferases inhibitor.

UOM: 1 * 10 mg

HMS Sertifikater Tilbud

Produsent: BEHR

Beskrivelse: Mineralisation workstation, Reaction vessel with NS 29 and marking at 100 ml, RG 1

Produsent: BEHR

Beskrivelse: Soxhlet-uttrekker, PTFE sleeves for RG 2, SR 2 and SR 2 Q, set of 12

New Product

Artikkenummer: (ANTIA250042-100)

Produsent: ANTIBODIES.COM

Beskrivelse: Mouse monoclonal [RG/26] antibody to beta III Spectrin for ELISA, WB, IF and IHC-P with samples derived from human, mouse and rat.

UOM: 1 * 1 Each

New Product Tilbud

Artikkenummer: (PRSI27-303)

Produsent: ProSci Inc.

Beskrivelse: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.

UOM: 1 * 1 Each

Tilbud

Artikkenummer: (PRSI27-990)

Produsent: ProSci Inc.

Beskrivelse: The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.

UOM: 1 * 1 Each

Tilbud

Artikkenummer: (PRSI27-222)

Produsent: ProSci Inc.

Beskrivelse: The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.

UOM: 1 * 1 Each

Tilbud

Artikkenummer: (PRSI27-991)

Produsent: ProSci Inc.

Beskrivelse: RGS13 encodes a protein which is a member of the regulator of G protein signaling (RGS) family. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation.

UOM: 1 * 1 Each

Tilbud

Artikkenummer: (PRSI29-804)

Produsent: ProSci Inc.

Beskrivelse: RGS8 is a member of the regulator of G protein signaling (RGS) family and is a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.

UOM: 1 * 1 Each

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