Du søkte etter: ENZO LIFE SCIENCES

Artikkenummer: (ENZOADIAAM080E)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: The Bcl-2 family of proteins regulate the intrinsic apoptotic pathway and are characterized by the sharing of at least one of four conserved Bcl-2 Homology (BH) domains.

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Artikkenummer: (ENZOADIAAP371E)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: TRAIL decoy receptors (DcR1, DcR2, and osteoprotegerin/OPG) completely or partially lack the signaling death domain, and/or are secreted from cells and unable to transmit intracellular signals.

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Artikkenummer: (ENZOADICSA512E)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs).

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Artikkenummer: (ENZOADICSA600F)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: CLIP (class II-associated invariant chain peptide) is an important peptide in the MHC-II antigen processing pathway, formed by the enzymatic cleavage of amino acids 81-104 from the invariant chain. During MHC-II synthesis in the ER and transport to endocytic vesicles, the antigen binding site of MHC-II is obstructed by the presence of the invariant chain. As the MHC-II complex moves through the Golgi, the invariant chain is degraded, leaving the CLIP fragment in the MHC-II peptide binding groove. CLIP is eventually displaced by the loading of antigenic peptides, followed by presentation on the APC cell surface to CD4+ T-cells.

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: Mcl-1 is a member of the Bcl-2 family that possesses anti-apoptotic activity. Mcl-1 is an immediate-early gene activated by the GMCSF as well as IL-3 signaling pathways and plays an important role in the viability response of these cytokines. Similar to all Bcl-2 family members, Mcl-1 contains BH1, BH2, and BH3 domains; however, unlike other members of this family, Mcl-1 has an extended N-terminal domain rich in PEST sequences, which probably accounts for the short half-life of this protein.

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Artikkenummer: (ENZOADIAAP330E)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Bim is a critical regulator of lymphocyte homeostasis, acts as a barrier against autoimmune disease and is necessary for the apoptotic response to certain stress signals.

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: Actin is one of the major proteins (~42 kDa) of the cytoskeleton. It regulates contractile potential in muscle tissues and helps to control the shape as well as the motility of non-muscle cells. Actin is expressed in all eukaryotic cells which makes it a useful loading control in Western blotting experiments. In higher eukaryotes, there are six isoforms of actin: Three alpha-actins (α-skeletal, α-cardiac, α-smooth muscle), one β-actin (β-non-muscle) and two γ-actins (γ-smooth muscle and γ-non-muscle). Actin isoforms show >90% overall sequence homology.

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Produsent: ENZO LIFE SCIENCES

Beskrivelse: The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

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Artikkenummer: (ENZOADIAAP110E)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors.

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Artikkenummer: (ENZOADICSA510E)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: MyD88 (Myeloid differentiation primary response gene 88) is a general adapter protein for the Toll/IL-1R family of receptors that have been shown to induce growth arrest, terminal differentiation, and apoptosis.

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Artikkenummer: (ENZOADICSA506E)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs recognize different pathogen-associated molecular patterns, thereby linking the innate and adaptive immune responses.

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Artikkenummer: (ENZOALX270275M005)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Inhibitor of CDK and GSK

UOM: 1 * 5 mg

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Artikkenummer: (ENZOADI900014)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Most sensitive (0,025pmol/m) colorimetric kit for intracellular cGMP quantification.

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Artikkenummer: (ENZOENZACC1020150)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: High sensitivity, low background streptavidin-based nanopolymer detection reagent for use with HIGHDEF® chromogens in ISH and IHC applications.

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Artikkenummer: (ENZOALX200421C005)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: MMP-8 is a glycoprotein containing complex N-linked oligosaccharides.

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Artikkenummer: (ENZOADI9002150001)

Produsent: ENZO LIFE SCIENCES

Beskrivelse: Rapid, easy-to-use ELISA kit to quantify 25(OH) Vitamin D for bone metabolism, nutrition, endocrinology, immunity and cancer.

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